منابع مشابه
-Linolenic acid and cardiovascular disease
Oomen et al (1) reported on the lack of association between -linolenic acid (ALA, 18:3n 3) consumption and the incidence of coronary artery disease in a 10-y follow-up. We believe that 2 major limitations of this study might have affected its outcome and led to the wrong conclusions. First, this study did not control for plasma concentrations of -linolenic acid; it is thus difficult to establis...
متن کاملCardiovascular Risk and -Linolenic Acid Can Costa Rica Clarify?
Interest is increasing in the potential cardioprotective role of -3 (n-3) fatty acids (FAs). Most of the evidence supporting this hypothesis has been derived from studies of the longer-chain members of the n-3 family, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), found in fish oils.1 The value of the shorter-chain cousin, -linolenic acid (ALA), found in certain plant oils (flaxsee...
متن کاملα-Linolenic acid, linoleic acid and heart failure in women.
α-Linolenic acid (18 : 3n-3) intake and linoleic acid (18 : 2n-6) intake have been associated with lower rates of CHD, though results have not been consistent. The relationship of these fatty acids with incident heart failure (HF) is not well established. We examined the hypothesis that women with higher intakes of 18 : 3n-3 and 18 : 2n-6 would have lower rates of HF hospitalisation and mortali...
متن کاملThe evidence for α-linolenic acid and cardiovascular disease benefits: Comparisons with eicosapentaenoic acid and docosahexaenoic acid.
Our understanding of the cardiovascular disease (CVD) benefits of α-linolenic acid (ALA, 18:3n-3) has advanced markedly during the past decade. It is now evident that ALA benefits CVD risk. The expansion of the ALA evidence base has occurred in parallel with ongoing research on eicosapentaenoic acid (EPA, 20:5n-3) and docosahexaenoic acid (DHA, 22:6n-3) and CVD. The available evidence enables c...
متن کاملAssociation between the intake of α-linolenic acid and the risk of CHD.
The intake of the mainly plant-derived n-3 PUFA α-linolenic acid (ALA) has been reported to be associated with a lower risk of CHD. However, the results have been inconsistent. Therefore, the objective of the present study was to examine the association between the intake of ALA and the risk of CHD. Potential effect modification by the intake of long-chain n-3 PUFA (n-3 LCPUFA) was also investi...
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ژورنال
عنوان ژورنال: Circulation
سال: 2008
ISSN: 0009-7322,1524-4539
DOI: 10.1161/circulationaha.108.791467